more Reliable

Ultralow (near-zero) carryover .

Ultralow carryover achieved without the need for rinsing

When rinsing is performed to keep carryover low, the total analysis
time sometimes increases as the number of analyses increases.
Nexera autosamplers excel in suppressing carryover even without rinsing.

Ultralow carryover even on a high-sensitivity LC/MS/MS

Ultralow carryover performance is required with
LC/MS systems. The SIL-30ACMP demonstrates
exceptional carryover performance even on
compounds such as chlorhexidine that are very
prone to adsorption. Moreover, the SIL-30ACMP
features an improved rinsing mechanism to achieve
even lower carryover.

Improvements in high-sensitivity analysis and quantitative precision achieved by ultralow carryover

In the batch analysis of multiple components, components with greatly differing polarities are frequently analyzed together. In cases such as this, sufficient rinsing may not be achieved using one type of rinse solution. To combat this, the SIL-30ACMP has not only been designed with a hardware structure to which components are less likely to adsorb, but also has a modified rinse mechanism designed to achieve even lower carryover.

Needle port rinsing mechanism

The needle port is one of the places on an autosampler where carryover is likely to occur. On the SIL-30ACMP, the needle port is rinsed automatically.

Multi-rinse mechanism supporting up to 4 solutions

The needle surface can be rinsed by a maximum of two rinse solutions and the needle inner surface can be rinsed by a maximum of three rinse solutions. Of course, rinsing with just one solution in the usual way is also possible. The rinsing order can also be set as desired.

Outstanding injection mechanism assures precision when injecting trace amounts

The SIL-30ACMP supports an injection volume range of 0.1 µL to 50 µL. Linearity is achieved within a broad injection range from injection of trace amounts required on a UHPLC up to the order of several tens of µL used on conventional models. The SIL-30ACMP provides excellent repeatability even in the injection of trace amounts of 1 µL or less.

As shown in the figure below, column sizes with an I.D. of approximately 2 mm, which are often used on a UHPLC, are susceptible to the influence of sample solvents, and it may be difficult to increase the injection volume. However, since the SIL-30ACMP is capable of high-precision injection of trace amounts, the influence of sample solvents can be suppressed even if pretreated organic solvent-rich samples are injected directly.

In the case of sample solvents having an elution strength greater than that of the mobile phase, the peak shape is sometimes deformed when the injection volume is increased.

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